Regulations and Restrictions

This resource provides a table of restricted substances lists and related laws and regulations organized by geographic scope. The linked substances lists provide descriptions of substances/chemicals that are legally or voluntarily restricted or recommended for restriction due to their hazards or have been examined by jurisdictions based on potential concerns of a similar nature. These lists of substances/chemicals can be of general interest for substitution activities.

world icon International Scope

Use the "Geographic Scope" identifier to find regulations and restrictions most relevant to your area.

Regulations and restrictions information is currently available for Canada, the People's Republic of China, the European Union, Japan, New Zealand, Singapore, Korea, Switzerland, the United States, international regulations, industry standards, and NGO-led programs.

Country Governing Body List of Substances of Interest Legislation/Program
Canada Government Virtual Elimination List as designated by Section 65 of CEPA Canadian Environmental Protection Act (CEPA), 1999
Toxic Substances List - Schedule 1
Regulations Amending the Prohibition of Certain Toxic Substances Regulations, 2012
Cosmetic Ingredient Hotlist: Prohibited and Restricted Ingredients Food and Drugs Act
People's Republic of ChinaGovernmentAnnouncement on the List of Toxic Chemicals Severely Restricted on the Import and Export in China (Circular No. 65 [2005])
Directions for the Registrations of Environmental Management on Import and Export of Toxic Chemicals
Amendment on the List of Toxic Chemicals Severely Restricted on Import and Export in China (Circular No. 80 [2006])
Announcement on the Catalogue of Commodities Prohibited from Import (The 6th Batch) and the Catalogue of Commodities Prohibited from Export (The 3rd Batch) (Circular No. 116 [2005])
Government (Hong Kong, China)Restricted substances under Schedule IHazardous Chemicals Control Ordinance, Chapter 595, Laws of Hong Kong
Restricted substances under Schedule II
European Union Government Annex II: List of prohibited substances (starts on page 25 in pdf) (2016 amendments to Annex II) EU Cosmetics Directive
Annex III: List of restricted substances (starts on page 128 in pdf) (2016 amendments to Annex III)
Registry of Intentions (RoI)Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)
Candidate List of Substances of Very High Concern (SVHC) for Authorisation
Authorisation List (Annex XIV)
Restriction List (Annex XVII)
List of restricted substancesRestriction of Hazardous Substances (RoHS) Directive
European Trade UnionTrade Union priority list for REACH authorizationBrochure Trade Union Priority List for REACH Authorisation - Version 2.0
JapanGovernmentClass I Specified Chemical SubstancesChemical Substances Control Law
Class II Specified Chemical Substances
Monitoring Chemical Substances
New ZealandGovernmentApproved Hazardous Substances with Controls
SingaporeGovernmentAdditional Hazardous Substances Controlled, January 2008Environmental Protection and Management Act
Additional Hazardous Substances Controlled, June 2009
Additional Hazardous Substances Controlled, August 2011
List of Controlled Chemicals in Pesticides
Hazardous Substances listed in Annex I
KoreaGovernmentList of restricted chemicalsAct on Registration and Evaluation of Chemical Substances (also known as K-REACH)
SwitzerlandGovernmentList of restricted substances814.81: Ordinance on the Reduction of Risks relating to the Use of Certain Particularly Dangerous Substances, Preparations and Articles 
Restrictions and Prohibitions in Annexes I & II
United States U.S. Environmental Protection Agency (EPA) List of 187 hazardous air pollutants designated by Section 112 Clean Air Act
National Emission Standards for Hazardous Air Pollutants (NESHAP)
List of Acutely Toxic Chemicals Emergency Planning and Community Right-to-Know Act (EPCRA)
List of Persistent, Bioaccumulative, Toxic (PBT) chemicals reportable under EPA’s Toxics Release Inventory (TRI) Program
List of 31 priority chemicals designated by the National Waste Minimization Program Resource Conservation and Recovery Act of 1976
Regulatory Determinations for Drinking Water Contaminant Candidate Lists Safe Drinking Water Act
List of 126 Priority Pollutants Clean Water Act
List of Class I Ozone Depleting Substances The Montreal Protocol
List of Class II Ozone Depleting Substances
List of Restricted Use Pesticides Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)
Regulatory actions for specific chemicals under the Toxic Substances Control Act Toxic Substances Control Act (TSCA)
U.S. Food and Drug Administration (FDA)List of chemicals restricted in cosmetic productsFDA Cosmetics Regulations
Agency for Toxics Substances & Disease Registry (ATSDR) under the U.S. Department of Health and Human Services (HHS)Priority List of Hazardous Substances That Will Be the Subject of Toxicological ProfilesComprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Section 104 (i) - note that CERCLA pertains to U.S. EPA and ATSDR
Department of Homeland Security (DHS)Chemicals of Concern listChemical Facility Anti-Terrorism Standards
Individual StatesDatabase of passed and pending state chemicals legislation from the Interstate Chemicals Clearinghouse (IC2)
InternationalOSPARList of Substances of Possible ConcernConvention for the Protection of the Marine Environment of the Northeast Atlantic
List of Chemicals for Priority Action
Stockholm Convention on Persistent Organic PollutantsList of chemical restricted by international treatyThe Stockholm Convention on Persistent Organic Pollutants
United NationsAnnex A: Controlled substancesThe Montreal Protocol on Substances that Deplete the Ozone Layer
Annex B: Controlled substances
Annex C: Controlled substances
Annex D: Products containing controlled substances specified in Annex A
Annex E: Controlled substances
List of restricted chemicals designated by Annex III of the Rotterdam ConventionFull Text of the Rotterdam Convention
List of restricted substances1998 Aarhus Protocol on Persistent Organic Pollutants
IndustryOEKO-TEXSTeP by OEKO-TEX: an independent test and certification system for textiles; contains methodology on hazardous chemical assessment and a restricted substances list.
American Chemistry CouncilThe Global Automotive Stakeholder Group's Global Automotive Declarable Substance List (GADSL)
Roadmap to ZeroList of prohibited substances
The International Fragrance Association (IFRA)List of restricted chemicalsInformation on the assessment of fragrances by the International Fragrance Association
Global Organic Textile StandardList of restricted substances
BluesignRestricted substances list
International Electrotechnical Commission (IEC)List of declarable substancesThe International Electrotechnical Commission's 62474 Standard (access by subscription only)
Non-Governmental OrganizationsChemSec (International Chemical Secretariat)The SIN (Substitute It Now!) List